Guangzhou will host Urawa Reds on October 23 at the Tianhe Stadium in Guangzhou in the second leg of the 2019 AFC Champions League semi-final.
Faghani has recently moved to Australia for personal reasons but said he will officiate as an Iranian referee.
Faghani, who started his career in 1994 and became a FIFA referee in 2008, has officiated finals of the 2014 AFC Champions League, 2015 AFC Asian Cup, 2015 FIFA Club World Cup and the 2016 Olympic Football Tournament.
He was also chosen to referee third-place playoff between Belgium and England in the 2018 FIFA World Cup.